U-Blot® EphA2/3/4 (phospho Tyr588/596) Polyclonal Antibody

Name: U-Blot® EphA2/3/4 (phospho Tyr588/596) Polyclonal Antibody
SKU: WP9582
Availability: InStock

$288.00

Size:50μL

SKU: WP9582-50

Catalog No.: WP9582

Specification: 50μL/100μL

Stock: In stock

U-Blot® EphA2/3/4 (phospho Tyr588/596) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010],

Product Overview

Catalog No.: WP9582
SKU: WP9582-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: EphA2/3/4
Reactivity: Human,Mouse,Rat
Application: WB,IF,ELISA
MW(Calculated): --
MW(Observed): 130kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human EPHA2/3 around the phosphorylation site of Tyr588/596. AA range:556-605
Sequence: --
Specificity: Phospho-EphA2/3/4 (Y588/596) Polyclonal Antibody detects endogenous levels of EphA2/3/4 protein only when phosphorylated at Y588/596.
Gene Name: EPHA2/3/4
Protein Name: Ephrin type-A receptor 2/3/4
Other Name: EPHA2;ECK;Ephrin type-A receptor 2;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK;EPHA3;ETK;ETK1;HEK;TYRO4;Ephrin type-A receptor 3;EPH-like kinase 4;EK4;hEK4;HEK;Human embryo kinase;Tyrosine-protein kinase TYRO
Organism-1: Human
Gene ID-1: 1969;2042;2043
SwissProt-1: P29317;P29320;P54764
Organism-2: Mouse
Gene ID-2: 13836;13838
SwissProt-2: --
Organism-3: Rat
Gene ID-3: 29210
SwissProt-3: O08680
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Single-pass type I membrane protein . Cell projection, ruffle membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell junction, focal adhesion . Present at regions of cell-cell contacts but also at the leading edge of migrating cells (PubMed:19573808, PubMed:20861311). Relocates from the plasma membrane to the cytoplasmic and perinuclear regions in cancer cells (PubMed:18794797). .