U-Blot® AMPKα1/2 (phospho Thr183/172) Polyclonal Antibody

Name: U-Blot® AMPKα1/2 (phospho Thr183/172) Polyclonal Antibody
SKU: WP9607
Availability: InStock

$288.00

Size:50μL

SKU: WP9607-50

Catalog No.: WP9607

Specification: 50μL/100μL

Stock: In stock

U-Blot® AMPKα1/2 (phospho Thr183/172) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9607
SKU: WP9607-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: AMPKα1/2
Reactivity: Human,Mouse,Rat,Monkey,Pig,Marsupenaeus japonicus
Application: IF,WB,IHC,ELISA
MW(Calculated): --
MW(Observed): 63kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;Not yet tested in other applications;
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Sequence: --
Specificity: Phospho-AMPKα1/2 (T183/172) Polyclonal Antibody detects endogenous levels of AMPKα1/2 protein only when phosphorylated at T183/172.
Gene Name: AAPK1/AAPK2
Protein Name: 5'-AMP-activated protein kinase catalytic subunit alpha-1/2
Other Name: PRKAA1;AMPK1;5'-AMP-activated protein kinase catalytic subunit alpha-1;AMPK subunit alpha-1;Acetyl-CoA carboxylase kinase;ACACA kinase;Hydroxymethylglutaryl-CoA reductase kinase;HMGCR kinase;Tau-protein kinase PRKAA1;PRKAA2;AMPK;
Organism-1: Human
Gene ID-1: 5562;5563
SwissProt-1: Q13131;P54646
Organism-2: Mouse
Gene ID-2: 105787;108079
SwissProt-2: --
Organism-3: Rat
Gene ID-3: 65248;78975
SwissProt-3: P54645;Q09137
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .