U-Blot® 4E-BP1 (phospho Ser65) Polyclonal Antibody

Name: U-Blot® 4E-BP1 (phospho Ser65) Polyclonal Antibody
SKU: WP9650
Availability: InStock

$288.00

Size:50μL

SKU: WP9650-50

Catalog No.: WP9650

Specification: 50μL/100μL

Stock: In stock

U-Blot® 4E-BP1 (phospho Ser65) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：eukaryotic translation initiation factor 4E binding protein 1(EIF4EBP1) Homo sapiens This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9650
SKU: WP9650-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: 4E-BP1
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 15kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human 4E-BP1 around the phosphorylation site of Ser64. AA range:30-79
Sequence: --
Specificity: Phospho-4E-BP1 (S64) Polyclonal Antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at S64.
Gene Name: EIF4EBP1
Protein Name: Eukaryotic translation initiation factor 4E-binding protein 1
Other Name: EIF4EBP1;Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1;eIF4E-binding protein 1;Phosphorylated heat- and acid-stable protein regulated by insulin 1;PHAS-I
Organism-1: Human
Gene ID-1: 1978
SwissProt-1: Q13541
Organism-2: Mouse
Gene ID-2: 13685
SwissProt-2: Q60876
Organism-3: Rat
Gene ID-3: 116636
SwissProt-3: Q62622
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: nucleoplasm,cytoplasm,cytosol,protein complex,