U-Blot® Cdc6 (phospho Ser54) Polyclonal Antibody

Name: U-Blot® Cdc6 (phospho Ser54) Polyclonal Antibody
SKU: WP9655
Availability: InStock

$288.00

Size:50μL

SKU: WP9655-50

Catalog No.: WP9655

Specification: 50μL/100μL

Stock: In stock

U-Blot® Cdc6 (phospho Ser54) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9655
SKU: WP9655-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Cdc6
Reactivity: Human,Mouse,Monkey
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 62kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human CDC6 around the phosphorylation site of Ser54. AA range:20-69
Sequence: --
Specificity: Phospho-Cdc6 (S54) Polyclonal Antibody detects endogenous levels of Cdc6 protein only when phosphorylated at S54.
Gene Name: CDC6
Protein Name: Cell division control protein 6 homolog
Other Name: CDC6;CDC18L;Cell division control protein 6 homolog;CDC6-related protein;Cdc18-related protein;HsCdc18;p62;cdc6;HsCDC6
Organism-1: Human
Gene ID-1: 990
SwissProt-1: Q99741
Organism-2: Mouse
Gene ID-2: 23834
SwissProt-2: O89033
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895). .