U-Blot® LAT (phospho Tyr191) Polyclonal Antibody

Name: U-Blot® LAT (phospho Tyr191) Polyclonal Antibody
SKU: WP9691
Availability: InStock

$288.00

Size:50μL

SKU: WP9691-50

Catalog No.: WP9691

Specification: 50μL/100μL

Stock: In stock

U-Blot® LAT (phospho Tyr191) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9691
SKU: WP9691-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: LAT
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 28kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human LAT around the phosphorylation site of Tyr191. AA range:191-240
Sequence: --
Specificity: Phospho-LAT (Y191) Polyclonal Antibody detects endogenous levels of LAT protein only when phosphorylated at Y191.
Gene Name: LAT
Protein Name: Linker for activation of T-cells family member 1
Other Name: LAT;Linker for activation of T-cells family member 1;36 kDa phospho-tyrosine adapter protein;pp36;p36-38
Organism-1: Human
Gene ID-1: 27040
SwissProt-1: O43561
Organism-2: Mouse
Gene ID-2: 16797
SwissProt-2: O54957
Organism-3: Rat
Gene ID-3: 81511
SwissProt-3: O70601
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Single-pass type III membrane protein . Present in lipid rafts.