U-Blot® NMDAε2 (phospho Tyr1474) Polyclonal Antibody

Name: U-Blot® NMDAε2 (phospho Tyr1474) Polyclonal Antibody
SKU: WP9695
Availability: InStock

$288.00

Size:50μL

SKU: WP9695-50

Catalog No.: WP9695

Specification: 50μL/100μL

Stock: In stock

U-Blot® NMDAε2 (phospho Tyr1474) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9695
SKU: WP9695-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: NMDAR2B
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 165kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human NMDAR2B around the phosphorylation site of Tyr1474. AA range:1435-1484
Sequence: --
Specificity: Phospho-NMDAε2 (Y1474) Polyclonal Antibody detects endogenous levels of NMDAε2 protein only when phosphorylated at Y1474.
Gene Name: GRIN2B
Protein Name: Glutamate [NMDA] receptor subunit epsilon-2
Other Name: GRIN2B;NMDAR2B;Glutamate [NMDA] receptor subunit epsilon-2;N-methyl D-aspartate receptor subtype 2B;NMDAR2B;NR2B;N-methyl-D-aspartate receptor subunit 3;NR3;hNR3
Organism-1: Human
Gene ID-1: 2904
SwissProt-1: Q13224
Organism-2: Mouse
Gene ID-2: 14812
SwissProt-2: Q01097
Organism-3: Rat
Gene ID-3: 24410
SwissProt-3: Q00960
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Late endosome . Lysosome . Cytoplasm, cytoskeleton . Co-localizes with the motor protein KIF17 along microtubules. .