U-Blot® PDE4B/C/D (phospho Ser133/119/190) Polyclonal Antibody

Name: U-Blot® PDE4B/C/D (phospho Ser133/119/190) Polyclonal Antibody
SKU: WP9700
Availability: InStock

$288.00

Size:50μL

SKU: WP9700-50

Catalog No.: WP9700

Specification: 50μL/100μL

Stock: In stock

U-Blot® PDE4B/C/D (phospho Ser133/119/190) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],

Product Overview

Catalog No.: WP9700
SKU: WP9700-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PDE4B/C/D
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 76kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human PDE4D around the phosphorylation site of Ser190/53. AA range:156-205
Sequence: --
Specificity: Phospho-PDE4B/C/D (S133/119/190) Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein only when phosphorylated at S133/119/190.
Gene Name: PDE4B/PDE4C/PDE4D
Protein Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Other Name: PDE4B;DPDE4;cAMP-specific 3';5'-cyclic phosphodiesterase 4B;DPDE4;PDE32;PDE4C;DPDE1;cAMP-specific 3',5'-cyclic phosphodiesterase 4C;DPDE1;PDE21;PDE4D;DPDE3;cAMP-specific 3',5'-cyclic phosphodiesterase 4D;DPDE3;PDE43
Organism-1: Human
Gene ID-1: 5144
SwissProt-1: Q07343;Q08493;Q08499
Organism-2: Mouse
Gene ID-2: 110385;238871
SwissProt-2: --
Organism-3: Rat
Gene ID-3: 24626;24627
SwissProt-3: P14646;P14644;P14270
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform PDE4B5]: Cytoplasm . Cell membrane .