U-Blot® Krs-1/2 (phospho Thr183) Polyclonal Antibody

Name: U-Blot® Krs-1/2 (phospho Thr183) Polyclonal Antibody
SKU: WP9727
Availability: InStock

$288.00

Size:50μL

SKU: WP9727-50

Catalog No.: WP9727

Specification: 50μL/100μL

Stock: In stock

U-Blot® Krs-1/2 (phospho Thr183) Polyclonal Antibody Learn more

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Background：serine/threonine kinase 3(STK3) Homo sapiens This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Product Overview

Catalog No.: WP9727
SKU: WP9727-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Krs-1/2
Reactivity: Human,Mouse
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 60kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Mst1/2 around the phosphorylation site of Thr183. AA range:149-198
Sequence: --
Specificity: Phospho-Krs-1/2 (T183) Polyclonal Antibody detects endogenous levels of Krs-1/2 protein only when phosphorylated at T183.
Gene Name: STK3/STK4
Protein Name: Serine/threonine-protein kinase 3/4
Other Name: STK3;KRS1;MST2;Serine/threonine-protein kinase 3;Mammalian STE20-like protein kinase 2;MST-2;STE20-like kinase MST2;Serine/threonine-protein kinase Krs-1;STK4;KRS2;MST1;Serine/threonine-protein kinase 4;Mammalian STE20-like prot
Organism-1: Human
Gene ID-1: 6789
SwissProt-1: Q13188;Q13043
Organism-2: Mouse
Gene ID-2: 56274;58231
SwissProt-2: --
Organism-3: Rat
Gene ID-3: 65189
SwissProt-3: O54748
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . The caspase-cleaved form cycles between nucleus and cytoplasm (PubMed:19525978, PubMed:11278283). Phosphorylation at Thr-117 leads to inhibition of nuclear translocation (PubMed:19525978). .