U-Blot® PAKγ (phospho Ser20) Polyclonal Antibody

Name: U-Blot® PAKγ (phospho Ser20) Polyclonal Antibody
SKU: WP9732
Availability: InStock

$288.00

Size:50μL

SKU: WP9732-50

Catalog No.: WP9732

Specification: 50μL/100μL

Stock: In stock

U-Blot® PAKγ (phospho Ser20) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9732
SKU: WP9732-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PAK2
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 62kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human PAK2 around the phosphorylation site of Ser20. AA range:5-54
Sequence: --
Specificity: Phospho-PAKγ (S20) Polyclonal Antibody detects endogenous levels of PAKγ protein only when phosphorylated at S20.
Gene Name: PAK2
Protein Name: Serine/threonine-protein kinase PAK 2
Other Name: PAK2;Serine/threonine-protein kinase PAK 2;Gamma-PAK;PAK65;S6/H4 kinase;p21-activated kinase 2;PAK-2;p58
Organism-1: Human
Gene ID-1: 5062
SwissProt-1: Q13177
Organism-2: Mouse
Gene ID-2: 224105
SwissProt-2: Q8CIN4
Organism-3: Rat
Gene ID-3: 100910732
SwissProt-3: Q64303
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Serine/threonine-protein kinase PAK 2]: Cytoplasm. MYO18A mediates the cellular distribution of the PAK2-ARHGEF7-GIT1 complex to the inner surface of the cell membrane.; [PAK-2p34]: Nucleus. Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane.