U-Blot® Cdk7 (phospho Thr170) Polyclonal Antibody

Name: U-Blot® Cdk7 (phospho Thr170) Polyclonal Antibody
SKU: WP9763
Availability: InStock

$288.00

Size:50μL

SKU: WP9763-50

Catalog No.: WP9763

Specification: 50μL/100μL

Stock: In stock

U-Blot® Cdk7 (phospho Thr170) Polyclonal Antibody Learn more

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Background：cyclin dependent kinase 7(CDK7) Homo sapiens The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9763
SKU: WP9763-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Cdk7
Reactivity: Human,Mouse
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 40kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human CDK7 around the phosphorylation site of Thr170. AA range:136-185
Sequence: --
Specificity: Phospho-Cdk7 (T170) Polyclonal Antibody detects endogenous levels of Cdk7 protein only when phosphorylated at T170.
Gene Name: CDK7
Protein Name: Cyclin-dependent kinase 7
Other Name: CDK7;CAK;CAK1;CDKN7;MO15;STK1;Cyclin-dependent kinase 7;39 kDa protein kinase;p39 Mo15;CDK-activating kinase 1;Cell division protein kinase 7;Serine/threonine-protein kinase 1;TFIIH basal transcription factor complex kinase subu
Organism-1: Human
Gene ID-1: 1022
SwissProt-1: P50613
Organism-2: Mouse
Gene ID-2: 12572
SwissProt-2: Q03147
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Cytoplasm, perinuclear region . Colocalizes with PRKCI in the cytoplasm and nucleus (PubMed:15695176). Translocates from the nucleus to cytoplasm and perinuclear region in response to DNA-bound peptides (PubMed:19071173). .