U-Blot® IκB-α (phospho Tyr305) Polyclonal Antibody

U-Blot® IκB-α (phospho Tyr305) Polyclonal Antibody
U-Blot® IκB-α (phospho Tyr305) Polyclonal Antibody
$288.00
Size:50μL
SKU: WP9784-50

Catalog No.: WP9784

Specification: 50μL/100μL

Stock: In stock

U-Blot® IκB-α (phospho Tyr305) Polyclonal Antibody Learn more

Product information

Background:This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],

Product Overview

Catalog No.
WP9784
SKU
WP9784-50
Category
Polyclonal antibodies
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
IκB-α
Reactivity
Human,Mouse,Rat,Monkey
Application
WB,IHC,IF,ELISA
MW(Calculated)
--
MW(Observed)
40kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Phospho
Modification site
--
Recommended Dilution Ratio
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
--
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone No.
--
Immunogen
The antiserum was produced against synthesized peptide derived from human IkappaB-alpha around the phosphorylation site of Tyr305. AA range:268-317
Sequence
--
Specificity
Phospho-IκB-α (Y305) Polyclonal Antibody detects endogenous levels of IκB-α protein only when phosphorylated at Y305.
Gene Name
NFKBIA IKBA MAD3 NFKBI
Protein Name
NF-kappa-B inhibitor alpha
Other Name
NFKBIA;IKBA;MAD3;NFKBI;NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3
Organism-1
Human
Gene ID-1
4792
SwissProt-1
P25963
Organism-2
Mouse
Gene ID-2
18035
SwissProt-2
Q9Z1E3
Organism-3
Rat
Gene ID-3
25493
SwissProt-3
Q63746
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Polyclonal antibodies