U-Blot® p70 S6 kinase α (phospho Thr412) Polyclonal Antibody

Name: U-Blot® p70 S6 kinase α (phospho Thr412) Polyclonal Antibody
SKU: WP9916
Availability: InStock

$288.00

Size:50μL

SKU: WP9916-50

Catalog No.: WP9916

Specification: 50μL/100μL

Stock: In stock

U-Blot® p70 S6 kinase α (phospho Thr412) Polyclonal Antibody Learn more

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Background：ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],

Product Overview

Catalog No.: WP9916
SKU: WP9916-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: p70 S6 kinase α
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 60kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Thr412. AA range:355-450
Sequence: --
Specificity: Phospho-p70 S6 kinase α (T412) Polyclonal Antibody detects endogenous levels of p70 S6 kinase α protein only when phosphorylated at T412.
Gene Name: RPS6KB1 STK14A P70S6K
Protein Name: Ribosomal protein S6 kinase beta-1
Other Name: RPS6KB1;STK14A;Ribosomal protein S6 kinase beta-1;S6K-beta-1;S6K1;70 kDa ribosomal protein S6 kinase 1;P70S6K1;p70-S6K 1;Ribosomal protein S6 kinase I;Serine/threonine-protein kinase 14A;p70 ribosomal S6 kinase alpha;p70 S6 kinas
Organism-1: Human
Gene ID-1: 6198
SwissProt-1: P23443
Organism-2: Mouse
Gene ID-2: 72508
SwissProt-2: Q8BSK8
Organism-3: Rat
Gene ID-3: 83840
SwissProt-3: P67999
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell junction, synapse, synaptosome . Mitochondrion outer membrane. Mitochondrion. Colocalizes with URI1 at mitochondrion.; [Isoform Alpha I]: Nucleus. Cytoplasm.; [Isoform Alpha II]: Cytoplasm.