U-Blot® PP2A-Cα (phospho Tyr307) Polyclonal Antibody

Name: U-Blot® PP2A-Cα (phospho Tyr307) Polyclonal Antibody
SKU: WP9920
Availability: InStock

$288.00

Size:50μL

SKU: WP9920-50

Catalog No.: WP9920

Specification: 50μL/100μL

Stock: In stock

U-Blot® PP2A-Cα (phospho Tyr307) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9920
SKU: WP9920-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PP2AA
Reactivity: Human,Mouse,Rat
Application: WB,IP,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 35kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human PP2A-alpha around the phosphorylation site of Tyr307. AA range:260-309
Sequence: --
Specificity: Phospho-PP2A-Cα (Y307) Polyclonal Antibody detects endogenous levels of PP2A-Cα protein only when phosphorylated at Y307.
Gene Name: PPP2CA
Protein Name: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Other Name: PPP2CA;Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;PP2A-alpha;Replication protein C;RP-C
Organism-1: Human
Gene ID-1: 5515
SwissProt-1: P67775
Organism-2: Mouse
Gene ID-2: 19052
SwissProt-2: P63330
Organism-3: Rat
Gene ID-3: 24672
SwissProt-3: P63331
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . In prometaphase cells, but not in anaphase cells, localizes at centromeres (PubMed:16541025). During mitosis, also found at spindle poles (PubMed:16541025). Centromeric localization requires the presence of SGO2 (By similarity). .