U-Blot® MLC-2 (phospho Thr17/S18) Polyclonal Antibody

Name: U-Blot® MLC-2 (phospho Thr17/S18) Polyclonal Antibody
SKU: WP9988
Availability: InStock

$288.00

Size:50μL

SKU: WP9988-50

Catalog No.: WP9988

Specification: 50μL/100μL

Stock: In stock

U-Blot® MLC-2 (phospho Thr17/S18) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014],

Product Overview

Catalog No.: WP9988
SKU: WP9988-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MLC-2
Reactivity: Human,Mouse,Rat
Application: IHC,IF,ELISA
MW(Calculated): 20kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human MLC-2 around the phosphorylation site of Thr17 and Ser18. AA range:5-54
Sequence: --
Specificity: Phospho-MLC-2 (T17/S18) Polyclonal Antibody detects endogenous levels of MLC-2 protein only when phosphorylated at T17/S18.
Gene Name: MYL12A
Protein Name: Myosin regulatory light chain 12A
Other Name: MYL12A;MLCB;MRLC3;RLC;Myosin regulatory light chain 12A;MLC-2B;Myosin RLC;Myosin regulatory light chain 2;nonsarcomeric;Myosin regulatory light chain MRLC3;MYL12B;MRLC2;MYLC2B;Myosin regulatory light chain 12B;MLC-2A;MLC-2;M
Organism-1: Human
Gene ID-1: 10398;10627
SwissProt-1: P19105;O14950;P24844
Organism-2: Mouse
Gene ID-2: 67938;98932
SwissProt-2: --
Organism-3: Rat
Gene ID-3: 50685;296313
SwissProt-3: P18666;Q64122
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: stress fiber,cytosol,brush border,myosin complex,myosin II complex,Z disc,apical part of cell,extracellular exosome,