U-Blot® ADAM10 Rabbit mAb

U-Blot® ADAM10 Rabbit mAb
U-Blot® ADAM10 Rabbit mAb
$268.00
Size:50μL
SKU: WR4488-50

Catalog No.: WR4488

Specification: 50μL/100μL

Stock: In stock

U-Blot® ADAM10 Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：ADAM metallopeptidase domain 10(ADAM10) Homo sapiens Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016],

Product Overview

Catalog No.
WR4488
SKU
WR4488-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
ADAM10
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
84kD
MW(Observed)
84kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT0709R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
ADAM10
Protein Name
Disintegrin and metalloproteinase domain-containing protein 10
Other Name
ADAM10;KUZ;MADM;Disintegrin and metalloproteinase domain-containing protein 10;ADAM 10;CDw156;Kuzbanian protein homolog;Mammalian disintegrin-metalloprotease;CD156c
Organism-1
Human
Gene ID-1
102
SwissProt-1
O14672
Organism-2
Mouse
Gene ID-2
11487
SwissProt-2
O35598
Organism-3
Rat
Gene ID-3
--
SwissProt-3
Q10743
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cell membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle . Cell projection, axon . Cell projection, dendrite . Cell junction, adherens junction . Cytoplasm . Is localized in the plasma membrane but is also expressed in the Golgi apparatus and in clathrin-coated vesicles derived likely from the Golgi (PubMed:12475894). During long term depression, it is recruited to the cell membrane by DLG1 (PubMed:23676497). The immature form is mainly located near cytoplasmic fibrillar structures, while the mature form is predominantly located at zonula adherens and the cell membrane (PubMed:30463011). The localization and clustering of mature ADAM10 to zonula adherens is regulated by AFDN, TSPAN33, PLEKHA7 and PDZD11 (PubMed:30463011). .

Tech Support

ucallm

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs