Sku: WR8148
U-Blot® PERK (Phospho Thr980) Rabbit mAb
Catalog No.: WR4598
Specification: 50μL/100μL
Stock: In stock
U-Blot® PERK (Phospho Thr980) Rabbit mAb Learn more
Product information
Background:The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
Product Overview
- Catalog No.
- WR4598
- SKU
- WR4598-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- PERK
- Reactivity
- Mouse,Rat
- Application
- WB,IF,ELISA
- MW(Calculated)
- 125kD
- MW(Observed)
- 125kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- --
- Clone No.
- PT0868R
- Immunogen
- --
- Sequence
- --
- Specificity
- PERK (Phospho Thr980) Antibody detects endogenous levels of PERK protein only when phosphorylated at T980.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):YArHT
- Gene Name
- EIF2AK3
- Protein Name
- Eukaryotic translation initiation factor 2-alpha kinase 3
- Other Name
- EIF2AK3;PEK;PERK;Eukaryotic translation initiation factor 2-alpha kinase 3;PRKR-like endoplasmic reticulum kinase;Pancreatic eIF2-alpha kinase;HsPEK
- Organism-1
- Human
- Gene ID-1
- 9451
- SwissProt-1
- Q9NZJ5
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q9Z2B5
- Organism-3
- Rat
- Gene ID-3
- 29702
- SwissProt-3
- Q9Z1Z1
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
