U-Blot® CDK1/2 (Phospho Thr14) Rabbit mAb

U-Blot® CDK1/2 (Phospho Thr14) Rabbit mAb
U-Blot® CDK1/2 (Phospho Thr14) Rabbit mAb
$288.00
Size:50μL
SKU: WR4632-50

Catalog No.: WR4632

Specification: 50μL/100μL

Stock: In stock

U-Blot® CDK1/2 (Phospho Thr14) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：cyclin dependent kinase 1(CDK1) Homo sapiens The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

Product Overview

Catalog No.
WR4632
SKU
WR4632-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
CDK1/CDC2 Phospho Thr14
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
34kD
MW(Observed)
34kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
--
Clone No.
PT0910R
Immunogen
--
Sequence
--
Specificity
Phospho-Cdk1/2 (T14) Antibody detects endogenous levels of Cdk1/2 protein only when phosphorylated at T14.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):EGtYG
Gene Name
CDK1/CDK2
Protein Name
Cyclin-dependent kinase 1/2
Other Name
CDK1;CDC2;CDC28A;CDKN1;P34CDC2;Cyclin-dependent kinase 1;CDK1;Cell division control protein 2 homolog;Cell division protein kinase 1;p34 protein kinase;CDK2;CDKN2;Cyclin-dependent kinase 2;Cell division protein kinase 2;p33 pr
Organism-1
Human
Gene ID-1
1017
SwissProt-1
P06493;P24941
Organism-2
Mouse
Gene ID-2
12534;12566
SwissProt-2
--
Organism-3
Rat
Gene ID-3
54237
SwissProt-3
P39951;Q63699
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Nucleus. Cytoplasm. Mitochondrion . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle. Cytoplasmic during the interphase. Colocalizes with SIRT2 on centrosome during prophase and on splindle fibers during metaphase of the mitotic cell cycle. Reversibly translocated from cytoplasm to nucleus when phosphorylated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs