Sku: WR8148
U-Blot® Drosha Rabbit mAb
Catalog No.: WR4660
Specification: 50μL/100μL
Stock: In stock
U-Blot® Drosha Rabbit mAb Learn more
Product information
Background:drosha ribonuclease III(DROSHA) Homo sapiens This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016],
Product Overview
- Catalog No.
- WR4660
- SKU
- WR4660-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Drosha
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 159kD
- MW(Observed)
- 159kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- --
- Clone No.
- PT0944R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- DROSHA
- Protein Name
- Ribonuclease 3
- Other Name
- DROSHA;RN3;RNASE3L;RNASEN;Ribonuclease 3;Protein Drosha;Ribonuclease III;RNase III;p241
- Organism-1
- Human
- Gene ID-1
- 29102
- SwissProt-1
- Q9NRR4
- Organism-2
- Mouse
- Gene ID-2
- 14000
- SwissProt-2
- Q5HZJ0
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Nucleus, nucleolus . A fraction is translocated to the nucleolus during the S phase of the cell cycle. Localized in GW bodies (GWBs), also known as P-bodies. .
Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
