Sku: WR8148
U-Blot® BRAT1 Rabbit mAb
Catalog No.: WR4716
Specification: 50μL/100μL
Stock: In stock
U-Blot® BRAT1 Rabbit mAb Learn more
Product information
Background:The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
Product Overview
- Catalog No.
- WR4716
- SKU
- WR4716-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- BRAT1
- Reactivity
- Human
- Application
- WB,IF,ICC,FC,IP
- MW(Calculated)
- --
- MW(Observed)
- 90kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-5000;ICC/IF 1:100-300;FC 1:100-300;IP 1:50-100
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT0803R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- BRAT1;BAAT1;C7orf27
- Protein Name
- BRCA1-associated ATM activator 1;BRCA1-associated protein required for ATM activation protein 1;
- Other Name
- BRAT1;BAAT1;C7orf27;BRCA1-associated ATM activator 1 ;BRCA1-associated protein required for ATM activation protein 1;
- Organism-1
- Human
- Gene ID-1
- 221927
- SwissProt-1
- Q6PJG6
- Organism-2
- --
- Gene ID-2
- --
- SwissProt-2
- --
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus. Cytoplasm. Note=Present at double strand breaks (DSBs)following ionizing radiation treatment. The ubiquitinated form localizes in the nucleus in a NDFIP1-dependent manner..
Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
