Sku: WR8148
U-Blot® TMEM43 Rabbit mAb
Catalog No.: WR4760
Specification: 50μL/100μL
Stock: In stock
U-Blot® TMEM43 Rabbit mAb Learn more
Product information
Background:This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008]
Product Overview
- Catalog No.
- WR4760
- SKU
- WR4760-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- TMEM43
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC
- MW(Calculated)
- 44kDa
- MW(Observed)
- 44kDa
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:200-1:1000;WB 1:1000-1:5000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- --
- Clone No.
- PT1120R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- TMEM43,UNQ2564/PRO6244
- Protein Name
- Transmembrane protein 43 (Protein LUMA)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 79188
- SwissProt-1
- Q9BTV4
- Organism-2
- Mouse
- Gene ID-2
- 74122
- SwissProt-2
- Q9DBS1
- Organism-3
- Rat
- Gene ID-3
- 362401
- SwissProt-3
- Q5XIP9
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:32614325}. Nucleus inner membrane; Multi-pass membrane protein. Cell membrane {ECO:0000269|PubMed:34050020}. Note=Retained in the inner nuclear membrane through interaction with EMD and A- and B-lamins. The N- and C-termini are oriented towards the nucleoplasm. The majority of the hydrophilic domain resides in the endoplasmic reticulum lumen (By similarity). {ECO:0000250}.
Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
