U-Blot® TMEM43 Rabbit mAb

U-Blot® TMEM43 Rabbit mAb
U-Blot® TMEM43 Rabbit mAb
$268.00
Size:50μL
SKU: WR4760-50

Catalog No.: WR4760

Specification: 50μL/100μL

Stock: In stock

U-Blot® TMEM43 Rabbit mAb Learn more

Product information

Background:This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008]

Product Overview

Catalog No.
WR4760
SKU
WR4760-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
TMEM43
Reactivity
Human,Mouse,Rat
Application
WB,IHC
MW(Calculated)
44kDa
MW(Observed)
44kDa
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:1000-1:5000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
--
Clone No.
PT1120R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
TMEM43,UNQ2564/PRO6244
Protein Name
Transmembrane protein 43 (Protein LUMA)
Other Name
--
Organism-1
Human
Gene ID-1
79188
SwissProt-1
Q9BTV4
Organism-2
Mouse
Gene ID-2
74122
SwissProt-2
Q9DBS1
Organism-3
Rat
Gene ID-3
362401
SwissProt-3
Q5XIP9
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:32614325}. Nucleus inner membrane; Multi-pass membrane protein. Cell membrane {ECO:0000269|PubMed:34050020}. Note=Retained in the inner nuclear membrane through interaction with EMD and A- and B-lamins. The N- and C-termini are oriented towards the nucleoplasm. The majority of the hydrophilic domain resides in the endoplasmic reticulum lumen (By similarity). {ECO:0000250}.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs