U-Blot® Ezrin/Radixin/Moesin (Phospho Thr567/Thr564/Thr558) Rabbit mAb

U-Blot® Ezrin/Radixin/Moesin (Phospho Thr567/Thr564/Thr558) Rabbit mAb
U-Blot® Ezrin/Radixin/Moesin (Phospho Thr567/Thr564/Thr558) Rabbit mAb
$288.00
Size:50μL
SKU: WR4817-50

Catalog No.: WR4817

Specification: 50μL/100μL

Stock: In stock

U-Blot® Ezrin/Radixin/Moesin (Phospho Thr567/Thr564/Thr558) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WR4817
SKU
WR4817-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Moesin/Ezrin/Radixin
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
69kD
MW(Observed)
65kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
Thr567/Thr564/Thr558)
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT0916R
Immunogen
--
Sequence
--
Specificity
Ezrin/Radixin/Moesin (Phospho Thr567/Thr564/Thr558) Antibody detects endogenous levels of Moesin/Ezrin/Radixin protein only when phosphorylated at Thr567/Thr564/Thr558.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):YKtLR
Gene Name
MSN
Protein Name
Moesin
Other Name
MSN;Moesin;Membrane-organizing extension spike protein;RDX;Radixin;EZR;VIL2;Ezrin;Cytovillin;Villin-2;p81
Organism-1
Human
Gene ID-1
4478;5962
SwissProt-1
P26038;P35241;P15311
Organism-2
Mouse
Gene ID-2
17698;19684;22350
SwissProt-2
--
Organism-3
Rat
Gene ID-3
81521;54319
SwissProt-3
O35763;P31977
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Function:Probably involved in connections of major cytoskeletal structures to the plasma membrane.,PTM:Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures.,similarity:Contains 1 FERM domain.,subcellular location:Phosphorylated form is enriched in microvilli-like structures at apical membrane.,subunit:In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation (By similarity). Binds SLC9A3R1.,tissue specificity:In all tissues and cultured cells studied.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs