U-Blot® NMDAR2B Rabbit mAb

U-Blot® NMDAR2B Rabbit mAb
U-Blot® NMDAR2B Rabbit mAb
$268.00
Size:50μL
SKU: WR4827-50

Catalog No.: WR4827

Specification: 50μL/100μL

Stock: In stock

U-Blot® NMDAR2B Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WR4827
SKU
WR4827-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
NMDAR2B
Reactivity
Human,Mouse,Rat
Application
WB,IF,ELISA
MW(Calculated)
166kD
MW(Observed)
190kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Ser380
Modification site
--
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT0999R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
GRIN2B
Protein Name
Glutamate [NMDA] receptor subunit epsilon-2
Other Name
GRIN2B;NMDAR2B;Glutamate [NMDA] receptor subunit epsilon-2;N-methyl D-aspartate receptor subtype 2B;NMDAR2B;NR2B;N-methyl-D-aspartate receptor subunit 3;NR3;hNR3
Organism-1
Human
Gene ID-1
2904
SwissProt-1
Q13224
Organism-2
Mouse
Gene ID-2
14812
SwissProt-2
Q01097
Organism-3
Rat
Gene ID-3
24410
SwissProt-3
Q00960
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Function:NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.,similarity:Belongs to the glutamate-gated ion channel (TC 1.A.10) family.,subunit:Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Found in a complex with GRIN1 and GRIN3B. Found in a complex with GRIN1, GRIN3A and PPP2CB. Interacts with PDZ domains of INADL and DLG4. Interacts with HIP1 (By similarity). Interacts with MAGI3.,tissue specificity:Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

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Keywords:Rabbit mAbs