U-Blot® Rb (Phospho Ser780) Rabbit mAb

U-Blot® Rb (Phospho Ser780) Rabbit mAb
U-Blot® Rb (Phospho Ser780) Rabbit mAb
$288.00
Size:50μL
SKU: WR4842-50

Catalog No.: WR4842

Specification: 50μL/100μL

Stock: In stock

U-Blot® Rb (Phospho Ser780) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WR4842
SKU
WR4842-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Rb
Reactivity
Human,Mouse,Rat
Application
WB,IF,IP,ELISA
MW(Calculated)
106kD
MW(Observed)
106kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
--
Recommended Dilution Ratio
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT0992R
Immunogen
--
Sequence
--
Specificity
Rb (Phospho Ser780) Antibody detects endogenous levels of Rb protein only when phosphorylated at S780.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TLsPI
Gene Name
RB1
Protein Name
Retinoblastoma-associated protein
Other Name
RB1;Retinoblastoma-associated protein;p105-Rb;pRb;Rb;pp110
Organism-1
Human
Gene ID-1
5925
SwissProt-1
P06400
Organism-2
Mouse
Gene ID-2
19645
SwissProt-2
P13405
Organism-3
Rat
Gene ID-3
24708
SwissProt-3
P33568
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Nucleus . During keratinocyte differentiation, acetylation by KAT2B/PCAF is required for nuclear localization. .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs