Sku: WR8148
U-Blot® PARK7 Rabbit mAb
Catalog No.: WR4910
Specification: 50μL/100μL
Stock: In stock
U-Blot® PARK7 Rabbit mAb Learn more
Product information
Background:The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],
Product Overview
- Catalog No.
- WR4910
- SKU
- WR4910-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- PARK7
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 20kD
- MW(Observed)
- 22kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:4000-1:20000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1140R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- PARK7
- Protein Name
- Protein DJ-1
- Other Name
- PARK7;Protein DJ-1;Oncogene DJ1;Parkinson disease protein 7
- Organism-1
- Human
- Gene ID-1
- 11315
- SwissProt-1
- Q99497
- Organism-2
- Mouse
- Gene ID-2
- 57320
- SwissProt-2
- Q99LX0
- Organism-3
- Rat
- Gene ID-3
- 117287
- SwissProt-3
- O88767
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cell membrane ; Lipid-anchor . Cytoplasm . Nucleus . Membrane raft . Mitochondrion . Endoplasmic reticulum . Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage (PubMed:18711745). Detected in tau inclusions in brains from neurodegenerative disease patients (PubMed:14705119). Membrane raft localization in astrocytes and neuronal cells requires palmitoylation. .
Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
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