U-Blot® PARK7 Rabbit mAb

U-Blot® PARK7 Rabbit mAb
U-Blot® PARK7 Rabbit mAb
$268.00
Size:50μL
SKU: WR4910-50

Catalog No.: WR4910

Specification: 50μL/100μL

Stock: In stock

U-Blot® PARK7 Rabbit mAb Learn more

Product information

Background:The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WR4910
SKU
WR4910-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
PARK7
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
20kD
MW(Observed)
22kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
IHC 1:4000-1:20000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1140R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
PARK7
Protein Name
Protein DJ-1
Other Name
PARK7;Protein DJ-1;Oncogene DJ1;Parkinson disease protein 7
Organism-1
Human
Gene ID-1
11315
SwissProt-1
Q99497
Organism-2
Mouse
Gene ID-2
57320
SwissProt-2
Q99LX0
Organism-3
Rat
Gene ID-3
117287
SwissProt-3
O88767
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cell membrane ; Lipid-anchor . Cytoplasm . Nucleus . Membrane raft . Mitochondrion . Endoplasmic reticulum . Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage (PubMed:18711745). Detected in tau inclusions in brains from neurodegenerative disease patients (PubMed:14705119). Membrane raft localization in astrocytes and neuronal cells requires palmitoylation. .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs