U-Blot® Gab 1 Rabbit mAb

U-Blot® Gab 1 Rabbit mAb
U-Blot® Gab 1 Rabbit mAb
$268.00
Size:50μL
SKU: WR4966-50

Catalog No.: WR4966

Specification: 50μL/100μL

Stock: In stock

U-Blot® Gab 1 Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：GRB2 associated binding protein 1(GAB1) Homo sapiens The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Product Overview

Catalog No.
WR4966
SKU
WR4966-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Gab 1
Reactivity
Human
Application
WB,IF,IP,ELISA
MW(Calculated)
77kD
MW(Observed)
110kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho Tyr1221/1222
Modification site
--
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1190R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
GAB1
Protein Name
GRB2-associated-binding protein 1
Other Name
GAB1;GRB2-associated-binding protein 1;GRB2-associated binder 1;Growth factor receptor bound protein 2-associated protein 1
Organism-1
Human
Gene ID-1
2549
SwissProt-1
Q13480
Organism-2
Mouse
Gene ID-2
14388
SwissProt-2
Q9QYY0
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Function:Probably involved in EGF and insulin receptor signaling.,PTM:Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.,similarity:Belongs to the GAB family.,similarity:Contains 1 PH domain.,subunit:Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs