Sku: WR8148
U-Blot® PFK-C Rabbit mAb
$268.00
Size:50μL
SKU: WR4976-50
Catalog No.: WR4976
Specification: 50μL/100μL
Stock: In stock
U-Blot® PFK-C Rabbit mAb Learn more
Product information
Background:This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
Product Overview
- Catalog No.
- WR4976
- SKU
- WR4976-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- PFK-C
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 86kD
- MW(Observed)
- 80kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1208R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- PFKP
- Protein Name
- 6-phosphofructokinase type C
- Other Name
- PFKP;PFKF;6-phosphofructokinase type C;6-phosphofructokinase;platelet type;Phosphofructo-1-kinase isozyme C;PFK-C;Phosphofructokinase 1;Phosphohexokinase
- Organism-1
- Human
- Gene ID-1
- 5214
- SwissProt-1
- Q01813
- Organism-2
- Mouse
- Gene ID-2
- 56421
- SwissProt-2
- Q9WUA3
- Organism-3
- Rat
- Gene ID-3
- 60416
- SwissProt-3
- P47860
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Catalytic activity:ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.,cofactor:Magnesium.,enzyme regulation:Allosteric enzyme activated by ADP, AMP, or fructose bisphosphate and inhibited by ATP or citrate.,miscellaneous:In human PFK exists as a system of 3 types of subunits, PFKM (muscle), PFKL (liver) and PFKP (platelet) isoenzymes.,pathway:Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.,similarity:Belongs to the phosphofructokinase family. Two domains subfamily.,subunit:Tetramer. Muscle is M4, liver is L4, and red cell is M3L, M2L2, or ML3. A subunit composition with a higher proportion of platelet type subunits is found in platelets, brain and fibroblasts.,
Tech Support
ucallm
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
06
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
