U-Blot® COX1 Rabbit mAb

U-Blot® COX1 Rabbit mAb
U-Blot® COX1 Rabbit mAb
$268.00
Size:50μL
SKU: WR4983-50

Catalog No.: WR4983

Specification: 50μL/100μL

Stock: In stock

U-Blot® COX1 Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Product Overview

Catalog No.
WR4983
SKU
WR4983-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
COX1
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
69kD
MW(Observed)
70kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Ser386
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1215R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
PTGS1
Protein Name
Prostaglandin G/H synthase 1
Other Name
PTGS1;COX1;Prostaglandin G/H synthase 1;Cyclooxygenase-1;COX-1;Prostaglandin H2 synthase 1;PGH synthase 1;PGHS-1;PHS 1;Prostaglandin-endoperoxide synthase 1
Organism-1
Human
Gene ID-1
5742
SwissProt-1
P23219
Organism-2
Mouse
Gene ID-2
19224
SwissProt-2
P22437
Organism-3
Rat
Gene ID-3
24693
SwissProt-3
Q63921
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Catalytic activity:Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group per subunit.,Function:May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.,miscellaneous:This enzyme acts both as a dioxygenase and as a peroxidase.,miscellaneous:This enzyme is the target of nonsteroidal anti-inflammatory drugs such as aspirin.,pathway:Lipid metabolism; prostaglandin biosynthesis.,similarity:Belongs to the prostaglandin G/H synthase family.,similarity:Contains 1 EGF-like domain.,subunit:Homodimer.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs