U-Blot® NUMB Rabbit mAb

U-Blot® NUMB Rabbit mAb
U-Blot® NUMB Rabbit mAb
$268.00
Size:50μL
SKU: WR5032-50

Catalog No.: WR5032

Specification: 50μL/100μL

Stock: In stock

U-Blot® NUMB Rabbit mAb Learn more

Product information

Background:The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

Product Overview

Catalog No.
WR5032
SKU
WR5032-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
NUMB
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
71kD
MW(Observed)
71kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1264R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
NUMB
Protein Name
Protein numb homolog
Other Name
NUMB;Protein numb homolog;h-Numb;Protein S171
Organism-1
Human
Gene ID-1
8650
SwissProt-1
P49757
Organism-2
Mouse
Gene ID-2
18222
SwissProt-2
Q9QZS3
Organism-3
Rat
Gene ID-3
--
SwissProt-3
Q2LC84
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Function:Implicated in the control of cell fate decisions during development.,PTM:Isoform 1 and isoform 2 are ubiquitinated by LNX leading to their subsequent proteasomal degradation (By similarity). Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,sequence Caution:Intron retention.,similarity:Contains 1 PID domain.,subunit:Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs