U-Blot® Nicastrin Rabbit mAb

Name: U-Blot® Nicastrin Rabbit mAb
SKU: WR5052
Availability: InStock

$268.00

Size:50μL

SKU: WR5052-50

Catalog No.: WR5052

Specification: 50μL/100μL

Stock: In stock

U-Blot® Nicastrin Rabbit mAb Learn more

U-Blot® Nicastrin Rabbit mAb

Target: NCSTN
Reactivity: Human,Mouse,Rat
Application: WB,IF,IP,ELISA
MW(Calculated): 78kD
MW(Observed): 110-120kD
Host Species: Rabbit
Isotype: IgG,Kappa
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: Protein A
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: PT1284R
Immunogen: --
Sequence: --
Specificity: Endogenous
Gene Name: NCSTN KIAA0253 UNQ1874/PRO4317
Protein Name: Nicastrin
Other Name: --
Organism-1: Human
Gene ID-1: 23385
SwissProt-1: Q92542
Organism-2: Mouse
Gene ID-2: 59287
SwissProt-2: P57716
Organism-3: Rat
Gene ID-3: 289231
SwissProt-3: Q8CGU6
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) . The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.

Tech Support

ucallm

Datasheet, COA, SDS, and protocol files can be requested from technical support.

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

Keywords:Rabbit mAbs