Sku: WR8148
U-Blot® TIM 3 Rabbit mAb
Catalog No.: WR5058
Specification: 50μL/100μL
Stock: In stock
U-Blot® TIM 3 Rabbit mAb Learn more
Product information
Background:The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011],
Product Overview
- Catalog No.
- WR5058
- SKU
- WR5058-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- TIM 3
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 33kD
- MW(Observed)
- 80kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Ser396
- Modification site
- Unmodified
- Recommended Dilution Ratio
- IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1293R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- HAVCR2 TIM3 TIMD3
- Protein Name
- Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell membrane protein 3) (TIM-3)
- Other Name
- TIM3;CD366;TIM-3;SPTCL;TIMD3;Tim-3;TIMD-3;HAVcr-2
- Organism-1
- Human
- Gene ID-1
- 84868
- SwissProt-1
- Q8TDQ0
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q8VIM0
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Membrane ; Single-pass type I membrane protein . Cell junction . Cell membrane . Localizes to the immunological synapse between CD8+ T-cells and target cells. .
Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
