U-Blot® RXRA Rabbit mAb

U-Blot® RXRA Rabbit mAb
U-Blot® RXRA Rabbit mAb
$268.00
Size:50μL
SKU: WR5065-50

Catalog No.: WR5065

Specification: 50μL/100μL

Stock: In stock

U-Blot® RXRA Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：retinoid X receptor alpha(RXRA) Homo sapiens Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014],

Product Overview

Catalog No.
WR5065
SKU
WR5065-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
RXRA
Reactivity
Human,Mouse,Rat
Application
WB,IF,IP,ELISA
MW(Calculated)
51kD
MW(Observed)
51kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1300R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
RXRA NR2B1
Protein Name
Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha)
Other Name
--
Organism-1
Human
Gene ID-1
6256
SwissProt-1
P19793
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
P28700
Organism-3
Rat
Gene ID-3
--
SwissProt-3
Q05343
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain.,Function:Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer.,online information:Retinoid X receptor entry,PTM:Sumoylated on Lys-108; which negatively regulates transcriptional activity. Desumoylated specifically by SENP6.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR2 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Homodimer or forms a heterodimer with peroxisome proliferator activated receptor gamma called adipocyte-specific transcription factor ARF6. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts with FAM120B (By similarity). Interacts with SFPQ. Interacts with HCV core protein. Interacts with PELP1. Interacts with SENP6. Interacts with DNTTIP2. Interacts with RNF8.,tissue specificity:Highly expressed in liver, also found in lung, kidney and heart.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs