Sku: WR8148
U-Blot® ARC Rabbit mAb
Catalog No.: WR5076
Specification: 50μL/100μL
Stock: In stock
U-Blot® ARC Rabbit mAb Learn more
Product information
Background:function:Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.,similarity:Belongs to the ARC/ARG3.1 family.,subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.,subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.,
Product Overview
- Catalog No.
- WR5076
- SKU
- WR5076-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- ARC
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 45kD
- MW(Observed)
- 55kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Ser396
- Modification site
- Unmodified
- Recommended Dilution Ratio
- IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1315R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- ARC KIAA0278
- Protein Name
- Activity-regulated cytoskeleton-associated protein (ARC/ARG3.1) (Activity-regulated gene 3.1 protein homolog) (Arg3.1)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 23237
- SwissProt-1
- Q7LC44
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q9WV31
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- Q63053
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Extracellular vesicle membrane ; Lipid-anchor . Cell junction, synapse, postsynaptic cell membrane ; Lipid-anchor . Cell junction, synapse . Cell junction, synapse, postsynaptic density . Early endosome membrane . Cell projection, dendrite . Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cell projection, dendritic spine . Cytoplasmic vesicle, secretory vesicle, acrosome . Forms virion-like extracellular vesicles that are released from neurons. Enriched in postsynaptic density of dendritic spines. Targeted to inactive synapses following interaction with CAMK2B in the kinase inactive state. Accumulation at weaker synapses may be required to prevent their undesired enhancement. Associated with the cell cortex of neuronal soma and dendrites (By similarity). Associated with the sperm tail (By similarity). .
Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
