U-Blot® SF2 Rabbit mAb

U-Blot® SF2 Rabbit mAb
U-Blot® SF2 Rabbit mAb
$268.00
Size:50μL
SKU: WR5082-50

Catalog No.: WR5082

Specification: 50μL/100μL

Stock: In stock

U-Blot® SF2 Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

U-Blot® SF2 Rabbit mAb

Product Overview

Catalog No.
WR5082
SKU
WR5082-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
SRSF1
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,ELISA
MW(Calculated)
28kD
MW(Observed)
28kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Ser2056
Modification site
--
Recommended Dilution Ratio
IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1323R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3
Protein Name
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Other Name
--
Organism-1
Human
Gene ID-1
6426
SwissProt-1
Q07955
Organism-2
Mouse
Gene ID-2
110809
SwissProt-2
Q6PDM2
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

Request Technical Support
Keywords:Rabbit mAbs