U-Blot® YAP (Phospho Ser397) Rabbit mAb

U-Blot® YAP (Phospho Ser397) Rabbit mAb
U-Blot® YAP (Phospho Ser397) Rabbit mAb
$288.00
Size:50μL
SKU: WR5095-50

Catalog No.: WR5095

Specification: 50μL/100μL

Stock: In stock

U-Blot® YAP (Phospho Ser397) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],

Product Overview

Catalog No.
WR5095
SKU
WR5095-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
YAP
Reactivity
Human,Mouse,Rat
Application
WB,IF,IP,ELISA
MW(Calculated)
54kD
MW(Observed)
65kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
Ser397
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1357R
Immunogen
--
Sequence
--
Specificity
YAP (Phospho Ser397) Antibody detects endogenous levels of YAP protein only when phosphorylated at Ser397.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DEsTD
Gene Name
YAP1 YAP65
Protein Name
Transcriptional coactivator YAP1
Other Name
Yorkie homolog;65 kDa Yes-associated protein;YAP65;
Organism-1
Human
Gene ID-1
10413
SwissProt-1
P46937
Organism-2
Mouse
Gene ID-2
22601
SwissProt-2
P46938
Organism-3
Rat
Gene ID-3
363014
SwissProt-3
Q2EJA0
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 WW domain.,subunit:Binds to the SH3 domain of the YES kinase. Binds to WBP1 and WBP2. Binds, in vitro, through the WW1 domain, to neural isoforms of ENAH that contain the PPSY motif.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs