U-Blot® Radixin Rabbit mAb

U-Blot® Radixin Rabbit mAb
U-Blot® Radixin Rabbit mAb
$268.00
Size:50μL
SKU: WR5117-50

Catalog No.: WR5117

Specification: 50μL/100μL

Stock: In stock

U-Blot® Radixin Rabbit mAb Learn more

Product information

Background:Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],

Product Overview

Catalog No.
WR5117
SKU
WR5117-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Radixin
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
69kD
MW(Observed)
80kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Thr286
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1325R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
RDX
Protein Name
Radixin
Other Name
RDX;Radixin
Organism-1
Human
Gene ID-1
5962
SwissProt-1
P35241
Organism-2
Mouse
Gene ID-2
19684
SwissProt-2
P26043
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Disease:Defects in RDX are the cause of non-syndromic sensorineural deafness autosomal recessive type 24 (DFNB24) [MIM:611022]. DFNB24 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.,Domain:The N-terminal domain interacts with the C-terminal domain of LAYN. An interdomain interaction between its N-terminal and C-terminal domains inhibits its ablilty to bind LAYN. In the presence of acidic phospholipids, the interdomain interaction is inhibited and this enhances binding to LAYN.,Function:Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.,PTM:Phosphorylated by tyrosine-protein kinases.,similarity:Contains 1 FERM domain.,subcellular location:Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively.,subunit:Binds SLC9A3R1. Interacts with NHERF1, NHERF2, LAYN, MME/NEP and ICAM2.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

Request Technical Support
Keywords:Rabbit mAbs