U-Blot® P2Y12 Rabbit mAb

U-Blot® P2Y12 Rabbit mAb
U-Blot® P2Y12 Rabbit mAb
$268.00
Size:50μL
SKU: WR5120-50

Catalog No.: WR5120

Specification: 50μL/100μL

Stock: In stock

U-Blot® P2Y12 Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],

Product Overview

Catalog No.
WR5120
SKU
WR5120-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
P2Y12
Reactivity
Human,Mouse,Rat
Application
WB,IF,IP,ELISA
MW(Calculated)
39kD
MW(Observed)
55kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Ser73/100
Modification site
--
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1329R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
P2RY12 HORK3
Protein Name
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)
Other Name
--
Organism-1
Human
Gene ID-1
64805
SwissProt-1
Q9H244
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
Q9CPV9
Organism-3
Rat
Gene ID-3
--
SwissProt-3
Q9EPX4
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Disease:Defects in P2RY12 are a cause of bleeding disorder [MIM:609821].,Function:Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Involved in platelets aggregation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs