U-Blot® eIF4E (Phospho Ser209) Rabbit mAb

U-Blot® eIF4E (Phospho Ser209) Rabbit mAb
U-Blot® eIF4E (Phospho Ser209) Rabbit mAb
$288.00
Size:50μL
SKU: WR5166-50

Catalog No.: WR5166

Specification: 50μL/100μL

Stock: In stock

U-Blot® eIF4E (Phospho Ser209) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.
WR5166
SKU
WR5166-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
eIF4E Phospho Ser209
Reactivity
Human,Mouse,Rat
Application
WB,IF,IP,ELISA
MW(Calculated)
25kD
MW(Observed)
25kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
--
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1400R
Immunogen
--
Sequence
--
Specificity
eIF4E (Phospho Ser209) Antibody detects endogenous levels of eIF4E protein only when phosphorylated at S209.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):SGsTT
Gene Name
EIF4E
Protein Name
Eukaryotic translation initiation factor 4E
Other Name
EIF4E;EIF4EL1;EIF4F;Eukaryotic translation initiation factor 4E;eIF-4E;eIF4E;eIF-4F 25 kDa subunit;mRNA cap-binding protein
Organism-1
Human
Gene ID-1
1977
SwissProt-1
P06730
Organism-2
Mouse
Gene ID-2
13684
SwissProt-2
P63073
Organism-3
Rat
Gene ID-3
117045
SwissProt-3
P63074
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm, P-body . Cytoplasm . Cytoplasm, Stress granule . Nucleus . Interaction with EIF4ENIF1/4E-T is required for localization to processing bodies (P-bodies) (PubMed:16157702, PubMed:24335285, PubMed:25923732). Imported in the nucleus via interaction with EIF4ENIF1/4E-T via a piggy-back mechanism (PubMed:10856257). .

Tech Support

ucallm

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs