- Target
- FLCN
- Reactivity
- Human
- Application
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 64kD
- MW(Observed)
- 70kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1578R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- FLCN BHD
- Protein Name
- Folliculin (BHD skin lesion fibrofolliculoma protein) (Birt-Hogg-Dube syndrome protein)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 201163
- SwissProt-1
- Q8NFG4
- Organism-2
- Mouse
- Gene ID-2
- 216805
- SwissProt-2
- Q8QZS3
- Organism-3
- Rat
- Gene ID-3
- 303185
- SwissProt-3
- Q76JQ2
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Lysosome membrane . Cytoplasm, cytosol . Cell projection, cilium . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Nucleus . Localizes to lysosome membrane in amino acid-depleted conditions and relocalizes to the cytosol upon refeeding (PubMed:24095279, PubMed:29848618, PubMed:31672913). Colocalizes with FNIP1 and FNIP2 in the cytoplasm (PubMed:17028174, PubMed:18663353). Also localizes to motile and non-motile cilia, centrosomes and the mitotic spindle (PubMed:23784378). .