U-Blot® D3DR Rabbit mAb

Background：This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain , which are associated with cognitive , emotional , and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms , although some variants may be subject to nonsense-mediated decay (NMD) . [provided by RefSeq , Jul 2008] ,