U-Blot® Pan-Serotonyl-Glutamine Rabbit pAb

Name: U-Blot® Pan-Serotonyl-Glutamine Rabbit pAb
SKU: WT9038
Availability: InStock

$750.00

Size:100μl

SKU: WT9038-100

Catalog No.: WT9038

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Background：Glutamine Serotonylation is a novel protein post-translational modification mediated by the neurotransmitter serotonin (5‑hydroxytryptamine, 5‑HT). Catalyzed by transglutaminases (TGases), this modification covalently conjugates serotonin to glutamine residues (Q) of target proteins, forming a stable Serotonyl‑Glutamine linkage. Serotonylation regulates the function of small GTPases, ion channels, cytoskeletal proteins, and various signaling proteins, and participates in critical physiological processes including cell secretion, contraction, migration, and signal transduction. It is closely associated with neural regulation, blood coagulation, inflammation, and the pathogenesis of multiple diseases, representing an important research area in post-translational modification studies.

Product Overview

Catalog No.: WT9038
SKU: WT9038-100
Category: Serotonylation
Product Type: Other
Size: 100μL/300μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: Store at -20°C. Avoid repeated freeze-thaw cycles
Research Use Only: Yes

Additional Specifications

Antibody Type: Polyclonal
Target: Serotonyl-Glutamine
Reactivity: Species Independent
Application: WB,IHC-P,ICC/IF,FC
MW(Calculated): Multiple
MW(Observed): Multiple
Host Species: Rabbit
Isotype: IgG
Conjugate: Unconjugated
Modification: Glutamine serotonylation
Modification Site: Gln（Q）
Recommended dilution ratio: WB 1:1000;IHC-P 1:100-1:200;ICC/IF 1:100-1:200;FC 1:100-1:200
Composition: PBS, Glycerol, BSA，NaN3
Purification process: Protein A
storageCondition: Store at -20°C. Avoid repeated freeze-thaw cycles
Stability: Stable for 12 months from date of receipt / reconstitution.
Concentration: --
Clonal: Polyclonal
Clone Number: --
Immunogen: polypeptide
Gene Name: --
Protein Name: --
Alternative name: Sero
Organism-1: --
Gene ID: --
SwissProt-1: --
--: Background：
Background: Glutamine Serotonylation is a novel protein post-translational modification mediated by the neurotransmitter serotonin (5‑hydroxytryptamine, 5‑HT). Catalyzed by transglutaminases (TGases), this modification covalently conjugates serotonin to glutamine residues (Q) of target proteins, forming a stable Serotonyl‑Glutamine linkage. Serotonylation regulates the function of small GTPases, ion channels, cytoskeletal proteins, and various signaling proteins, and participates in critical physiological processes including cell secretion, contraction, migration, and signal transduction. It is closely associated with neural regulation, blood coagulation, inflammation, and the pathogenesis of multiple diseases, representing an important research area in post-translational modification studies.
Cellular Localization: --
--: Background：Glutamine Serotonylation is a novel protein post-translational modification mediated by the neurotransmitter serotonin (5‑hydroxytryptamine, 5‑HT). Catalyzed by transglutaminases (TGases), this modification covalently conjugates serotonin to glutamine residues (Q) of target proteins, forming a stable Serotonyl‑Glutamine linkage. Serotonylation regulates the function of small GTPases, ion channels, cytoskeletal proteins, and various signaling proteins, and participates in critical physiological processes including cell secretion, contraction, migration, and signal transduction. It is closely associated with neural regulation, blood coagulation, inflammation, and the pathogenesis of multiple diseases, representing an important research area in post-translational modification studies.
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