Ucell™ 6 Well Cell Culture Plate, Laminin, Clear, Flat bottom, Sterile

Laminin is an important component of the extracellular matrix, which is present in the basal side of all epithelial cells and endothelial cells, and is also the intermediary of some cell-to-cell interactions. Laminin is essential for biological activity, affecting cell differentiation, growth, migration and adhesion. Laminin is a multi-domain trioglycan protein of extracellular matrix, which is the main non-collagenous component of the basal layer and supports adhesion, proliferation and differentiation. Laminin consists of chains A, B1, and B2, which are connected by a number of disulfide bonds. It consists of three long polypeptide chains (called alpha, beta, and gamma) that are linked together by disulfide bonds and arranged in an asymmetrical cross shape. Laminin acts as a glue that holds the cells and ECM together. It has active domains of collagen binding, cell adhesion, heparin binding and outgrowing segments of neurites. Laminin regulates cell growth, motility, and signaling pathways Laminin supports the growth and differentiation of multiple cell types, including epithelial, endothelial, nerve, muscle, and liver cells. Laminin 521 has emerged as the most promising coating system for large-scale expansion of induced pluripotent stem cells (IPscs). ·Pre-coated biocoatings save time and money on experiment preparation ·Batch to batch stability ensures repeatability of experimental results ·Provides a variety of ready-to-use coated products to meet customers' different experimental needs ·Each packaging bag is printed with the batch number, easy to trace the quality ·Irradiation sterilization, SAL10-6, DNase/RNase free, pyrogen free