Sku: PR00174
Recombinant Human HMGB2 Protein, C-His
$210.00
Size:10μg
SKU: PR00106-10μg
Catalog No.: PR00106
Specification: 10μg/50μg/500μg/1mg
Stock: In stock
Product details, specifications, documents, and related products are available from the catalog record. Learn more
Product information
Background:High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Product Overview
- Catalog No.
- PR00106
- SKU
- PR00106-10μg
- Category
- High Mobility Group superfamily
- Product Type
- Other
- Size
- 10μg/50μg/500μg/1mg
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Research Use Only
- Yes
Additional Specifications
- Molecule
- HMGB2
- Background
- High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
- Species
- Human
- Source
- HEK293 Cells
- Tags
- C-6His
- Accession
- P26583
- KnownAs
- High Mobility Group Protein B2; High Mobility Group Protein 2; HMG-2; HMGB2; HMG2
- Protein Length
- Gly2-Glu209
- Predicted Molecular Mass
- 25.07 KDa
- N-terminal Sequence
- --
- SDS-PAGE
- 28 KDa, reducing conditions
- Endotoxin
- <1 EU/µg as determined by LAL test.
- Concentration
- --
- Purity-SDS-PAGE
- >95% as determined by SDS-PAGE.
- Purity-SEC-HPLC
- --
- Activity
- --
- Form
- Lyophilized
- Formulation
- Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.
- Shipping
- The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
- Storage
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
- Reconstitution
- Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.
Tech Support
ucallm
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Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
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