Sku: PR00174
Recombinant Human HMGB1 Protein, N-teminal
$210.00
Size:10μg
SKU: PR00143-10μg
Catalog No.: PR00143
Specification: 10μg/50μg/500μg/1mg
Stock: In stock
Product details, specifications, documents, and related products are available from the catalog record. Learn more
Product information
Background:High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
Product Overview
- Catalog No.
- PR00143
- SKU
- PR00143-10μg
- Category
- High Mobility Group superfamily
- Product Type
- Other
- Size
- 10μg/50μg/500μg/1mg
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Research Use Only
- Yes
Additional Specifications
- Molecule
- HMGB1
- Background
- High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
- Species
- Human
- Source
- E. coli
- Tags
- Tag free
- Accession
- P09429
- KnownAs
- High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1
- Protein Length
- Met1-Phe89
- Predicted Molecular Mass
- 10.4 KDa
- N-terminal Sequence
- --
- SDS-PAGE
- 14 KDa, reducing conditions
- Endotoxin
- <1 EU/µg as determined by LAL test.
- Concentration
- --
- Purity-SDS-PAGE
- --
- Purity-SEC-HPLC
- --
- Activity
- --
- Form
- Lyophilized
- Formulation
- Lyophilized from a 0.2 μm filtered solution of 50mM HEPES, 500mM NaCl, 0.5mMDTT, pH 7.9 .
- Shipping
- The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
- Storage
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
- Reconstitution
- Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.
Tech Support
ucallm
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Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
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