Recombinant Mouse CD137/TNFRSF9/4-1BB Protein, C-His

Recombinant Mouse CD137/TNFRSF9/4-1BB Protein, C-His
Recombinant Mouse CD137/TNFRSF9/4-1BB Protein, C-His
$9,999.00
Size:10μg
SKU: PR02709-10μg

Catalog No.: PR02709

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.

Product Overview

Catalog No.
PR02709
SKU
PR02709-10μg
Category
Tumor Necrosis Factors
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
TNFRSF9/4-1BB/CD137
Background
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Species
Mouse
Source
HEK293 Cells
Tags
C-6His
Accession
P20334
KnownAs
4-1BB ligand receptor; T-cell antigen 4-1BB; CD137; Tnfrsf9
Protein Length
Val24-Leu187
Predicted Molecular Mass
18.4 KDa
N-terminal Sequence
--
SDS-PAGE
24-38 KDa, reducing conditions
Endotoxin
<1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>95% as determined by reducing SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 1 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Tumor Necrosis Factors