U-Blot® CDH6 hIgG1 Reference Antibody (Ralubio)

Background:CDH6, also known as K-cadherin, belongs to type II cadherin and is composed of three distinct domains, an extracellular domain (ECD) containing five cadherin sequences, a transmembrane region, and an intracellular tail. CDH6 is highly expressed in many malignant tumors (human renal cell carcinoma, ovarian cancer, thyroid cancer, cholangiocarcinoma, and small cell lung cancer), and overexpression of CDH6 protein has a worse prognosis than cases with low or no CDH6 protein expression. Therefore, it can be used to target CDH6 related small molecule drugs or monoclonal antibodies, double antibodies.