U-Blot® PD1 hIgG1 Reference Antibody(Rosnbio)

Background:Programmed cell death protein-1 (PD-1) is an inhibitory immune checkpoint primarily expressed by immune cells. In the tumor microenvironment, PD-1 binds to its ligands PD-L1 and PD-L2, inhibiting T cell activation and proliferation, which allows tumor cells to evade immune system surveillance. As a novel agonist, Rosnilimab offers a new approach for T cell immune activation and may open new avenues for the treatment of tumors and autoimmune diseases.