U-Blot® TNFSF13B(BAFF) hIgG1 Reference Antibody (Belibio)

Background:BAFF (B-cell Activating Factor), also known as BLYS, CD257, TALL-1, THANK, and TNFSF20, is a member of the tumor necrosis factor superfamily, encoded by the TNFSF13B gene. Belimumab, a monoclonal antibody targeting BAFF, is marketed under the name Benlysta and is the first biologic globally approved for the treatment of systemic lupus erythematosus (SLE). Belimumab blocks the interaction of BAFF with its receptors (BAFF-R, TACI, and BCMA), thereby reducing B cell activation and the production of autoreactive antibodies.