U-Blot® DR5 mouse mAb

Name: U-Blot® DR5 mouse mAb
SKU: WM0674
Availability: InStock

$268.00

Size:50μL

SKU: WM0674-50

Catalog No.: WM0674

Specification: 50μL/100μL

Stock: In stock

U-Blot® DR5 mouse mAb Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009],

Product Overview

Catalog No.: WM0674
SKU: WM0674-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: DR5
Reactivity: Human,Mouse
Application: WB,ICC
MW(Calculated): --
MW(Observed): 48kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ICC 1:100
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human DR5 protein fragments expressed in E.coli.
Sequence: --
Specificity: This antibody detects endogenous levels of DR5 and does not cross-react with related proteins.
Gene Name: tnfrsf10b
Protein Name: Tumor necrosis factor receptor superfamily member 10B
Other Name: Fas like protein;Apoptosis inducing protein TRICK2A/2B;Apoptosis inducing receptor TRAIL R2;CD 262;CD262;CD262 antigen;Cytotoxic TRAIL receptor 2;Death domain containing receptor for TRAIL/Apo 2L;Death domain containing receptor for TRAIL/Apo2L;Death receptor 5;DR 5;DR5;Fas like protein precursor;KILLER;KILLER/DR5;OTTHUMP00000123492;OTTHUMP00000123493;p53 regulated DNA damage inducible cell death receptor;killer;p53 regulated DNA damage inducible cell death receptor;killer;TNF related apoptosis inducing ligand receptor 2;TNF related apoptosis inducing ligand receptor 2;TNF-related apoptosis-inducing ligand receptor 2;TNFRSF10B;TR10B_HUMAN;TRAIL R2;TRAIL receptor 2;TRAIL-R2;TRAILR2;TRANCER;TRICK2;TRICK2A;TRICK2B;TRICKB;Tumor necrosis factor receptor like protein ZTNFR9;Tumor necrosis factor receptor like protein ZTNFR9;Tumor necrosis factor receptor superfamily member 10b;Tumor necrosis factor receptor superfamily, member 10b;ZTNFR9.
Organism-1: Human
Gene ID-1: 8795
SwissProt-1: O14763
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q9QZM4
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Membrane; Single-pass type I membrane protein.