U-Blot® RPA32/RPA2 mouse mAb

Name: U-Blot® RPA32/RPA2 mouse mAb
SKU: WM0694
Availability: InStock

$268.00

Size:50μL

SKU: WM0694-50

Catalog No.: WM0694

Specification: 50μL/100μL

Stock: In stock

U-Blot® RPA32/RPA2 mouse mAb Learn more

Product details Specifications Q & A Education

Background：function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,

Product Overview

Catalog No.: WM0694
SKU: WM0694-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RFA2
Reactivity: Human
Application: WB,IP,ICC
MW(Calculated): --
MW(Observed): 32kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:2000;ICC 1:200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human RPA32/RPA2 protein fragments expressed in E.coli.
Sequence: --
Specificity: This antibody detects endogenous levels of RPA32/RPA2 and does not cross-react with related proteins.
Gene Name: rpa2
Protein Name: --
Other Name: 60S acidic ribosomal protein P1;AA409079;AI325195;AU020965;HSSB;ik:tdsubc_2g1;M;2;21C;MGC137236;OTTHUMP00000004008;p32;p34;RCJMB04_6d17 replication protein A2, 32kDa;REPA 2;REPA1;REPA2;Replication factor A protein 2;Replication protein A 32 kDa subunit;Replication protein A 32kDa subunit;Replication protein A 34 kDa subunit;Replication protein A;replication protein A1;70kD;Replication Protein A2;32kDa;Replication protein A2 32kD;Replication protein A2 32kDa;Replication protein A2;Replication protein A2, 32kDa;RF A;RF-A protein 2;Rf-A2;RFA;RFA2_HUMAN;RP A;RP-A p32;RP-A p34;RP21C;RPA 2;RPA 32;RPA;RPA2;RPA32;RPA34;RPA70;RpLP1;RpP2;xx:tdsubc_2g1;zgc:109822.
Organism-1: Human
Gene ID-1: 6118
SwissProt-1: P15927
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q62193
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .