U-Blot® Bag1 mouse mAb

Name: U-Blot® Bag1 mouse mAb
SKU: WM0716
Availability: InStock

$268.00

Size:50μL

SKU: WM0716-50

Catalog No.: WM0716

Specification: 50μL/100μL

Stock: In stock

U-Blot® Bag1 mouse mAb Learn more

Product details Specifications Q & A Education

Background：The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010],

Product Overview

Catalog No.: WM0716
SKU: WM0716-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Bag1
Reactivity: Human,Mouse(predicted:Rat,
Application: WB
MW(Calculated): --
MW(Observed): 52,46，33kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human Bag1 protein fragments expressed in E.coli.
Sequence: --
Specificity: Transfected
Gene Name: bag1
Protein Name: BAG family molecular chaperone regulator 1
Other Name: Bag 1;BAG family molecular chaperone regulator 1;BAG-1;BAG1;BAG1_HUMAN;BCL 2 Associated Athanogene 1;BCL 2 associated athanogene;BCL 2 binding athanogene 1;Bcl-2-associated athanogene 1;BCL2 associated athanogene 1;BCL2 associated athanogene;Glucocorticoid receptor-associated protein RAP46;HAP1;Haptoglobin;RAP 46;RAP46.
Organism-1: Human
Gene ID-1: 573
SwissProt-1: Q99933
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q60739
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Nucleus. Cytoplasm. Isoform 1 localizes predominantly to the nucleus.; [Isoform 2]: Cytoplasm. Nucleus. Isoform 2 localizes to the cytoplasm and shuttles into the nucleus in response to heat shock.; [Isoform 4]: Cytoplasm. Nucleus. Isoform 4 localizes predominantly to the cytoplasm. The cellular background in which it is expressed can influence whether it resides primarily in the cytoplasm or is also found in the nucleus. In the presence of BCL2, localizes to intracellular membranes (what appears to be the nuclear envelope and perinuclear membranes) as well as punctate cytosolic structures suggestive of mitochondria.